testaboutus
Founded on science.
Driven by patients.
“Alethio Therapeutics was born from years of research at the University of Oxford and from our direct experience treating patients with MPNs. We founded the company to ensure that deep human disease insight and rigorous science translate into medicines that can alter disease progression, not just manage its symptoms. Our aim is to offer patients real hope — helping them live longer, healthier lives.”
Co-founders Professors Adam Mead and Beth Psaila
Our Team
Management Team, Founders and Board of Directors
Dr Rohit Batta
CEO
Dr Rohit Batta
CEO
Rohit is a medical doctor with 20 years of drug development experience, the majority of which has been dedicated to rare diseases. His career spans early discovery through to global launch and reimbursement.
Rohit joined Alethio Therapeutics from Ferring Ventures where he served as Managing Director and Head of the group. Prior to that he served as CMO at the publicly listed Vicore Pharma and spent a decade at GSK in senior leadership roles within the global rare disease organization. At GSK, he led the clinical strategy for hemoglobinopathy gene therapies and played a pivotal role in launching the world’s first gene therapy for a pediatric rare disease – an achievement that earned his team the prestigious Prix Galien award.
He began his career as a physician in the UK’s National Health Service, working across multiple clinical specialties including oncology, experience that continues to inform his patient centred approach to innovation.
Dr Ed Ainscow
CSO
Dr Ed Ainscow
CSO
Ed brings nearly 20 years of experience in early drug discovery gained at large pharma and emerging biotech companies. He spent nine years at AstraZeneca, during which time he specialized in the application of high throughput imaging in drug discovery screening. He later joined the Genomics Institute of the Novartis Research Foundation as Associate Director of Assay Development and High Throughput Screening.
Prior to Joining Alethio Therapeutics, Ed worked for five years heading drug discovery activities at Carrick Therapeutics, an oncology-focused biotechnology company.
Ed has degrees in Biochemistry and his early career centred on the study of hepatic and islet metabolism.
Dr Steve Coats
CDO
Dr Steve Coats
CDO
Steve Coats is a seasoned biopharmaceutical R&D leader with over 30 years of experience advancing monoclonal antibody (mAb) and antibody–drug conjugate (ADC) therapies from discovery through clinical development. He has led multidisciplinary nonclinical, clinical, CMC, and technology teams across multiple biologics platforms and therapeutic areas.
Most recently, Steve served as Chief Development Officer at ImmunOs Therapeutics (2021–2024), directing development of immunology focused biologics. Prior to that, he spent more than 15 years at AstraZeneca/MedImmune, ultimately as VP of R&D, where he led global teams delivering multiple novel biologics and ADCs and through IND/CTA submission and into proof of concept Phase 2 trials. Earlier in his career, he was a Research Director at Amgen, leading both small molecule and biologics discovery programmes.
In recent years, Steve has worked as a strategic consultant supporting startups and mid stage biotech companies with early stage financing, clinical development strategy, and venture capital due diligence.
Steve completed postdoctoral training at the Fred Hutchinson Cancer Research Center, focusing on signal transduction and cellcycle biology. He holds a Ph.D. in Molecular and Cell Biology from Vanderbilt University and a B.A. from the University of New Hampshire.
Mike Grey
Chair
Mike Grey
Chair
Mike has founded five biotechnology companies and is currently chairman or executive chair of Mirum Pharmaceuticals, Sorriso Pharmaceuticals, Spruce Biosciences, Theolytics, Plexium and Alethio Therapeutics. He also serves as venture partner at Pappas Capital.
In a career spanning over 50 years, Mike has held senior positions at a number of companies, including CEO of Amplyx Pharmaceuticals (acquired by Pfizer), Lumena Pharmaceuticals, (acquired by Shire), Auspex Pharmaceuticals, SGX Pharmaceuticals. (acquired by Eli Lilly) and Trega Biosciences. (acquired by Lion Bioscience), as well as president of BioChem Therapeutic. Mike also spent 20 years in various roles with Glaxo and Glaxo Holdings (now GSK), culminating in his position as Vice President, Corporate Development and Head of International Licensing.
Prof. Beth Psaila
Founder and Director
Prof. Beth Psaila
Founder and Director
Beth is a Professor of Haematology at the University of Oxford where she leads a laboratory focused on two research areas – understanding disease mechanisms in myeloproliferative neoplasms, and studying the cell biology of megakaryocytes and platelets, and their roles in cancer.
Beth spends a significant amount of her time in the clinic, specialising in the care of patients with myeloproliferative neoplasms. She leads a portfolio of clinical trials with a particular focus on emerging MPN targeted therapies and is Chair of the National UK Blood Cancer Research Network MPN Subgroup – a working party responsible for co-ordinating national delivery of clinical trials, guidelines/educational initiatives, and real-world data collections.
Prof. Adam Mead
Founder and Board Observer
Prof. Adam Mead
Founder and Board Observer
Adam is Professor of Haematology at the University of Oxford. He is a practising clinician-scientist whose research focuses on myeloproliferative neoplasms (MPN), a group of blood cancers that are incurable with conventional treatment. He has led more than 60 clinical studies and previously chaired the UK national MPN trials group.
Adam leads a CRUK funded research group at the MRC Weatherall Institute of Molecular Medicine (WIMM), with a focus on discovering novel and rational therapeutic strategies to address the unmet clinical needs of people with MPN. His group applies single-cell multi-omics, experimental models and analysis of patient samples to define disease-driving stem-cell programmes and therapeutic vulnerabilities. He co-founded the Oxford spin-out Alethio Therapeutics to translate laboratory discoveries into first-in-human studies, and he co-leads the Oxford CRUK Cancer Centre’s myeloid programme.
Dr Mark Throsby
Non-Executive Director
Dr Mark Throsby
Non-Executive Director
Mark has spent more than 25 years in biotech with extensive research experience and a track record of innovation and execution. He gained a Ph.D. in Immunology from Monash University (Melbourne, Australia) and spent four years as a research fellow with CNRS in Paris. Mark started his industry career at the formation of Crucell and worked there for eight years in various roles, finally as Director of Antibody Discovery. He joined Merus in 2008 as CSO supporting the development of its bispecific antibody platform and leading preclinical research until 2020. Since 2020 he has held executive management or board positions in preclinical- and clinical-stage biotechnology companies throughout Europe including ONA Therapeutics, Gadeta and Montis Biosciences. He is Executive Chair of ATB Therapeutics.
Dr Suman Shirodkar
Non-Executive Director
Dr Suman Shirodkar
Non-Executive Director
Suman has over 25 years of experience in the pharmaceutical and biotech industries with expertise in cardiovascular, oncology, immunology and anti-viral therapeutic areas. She has worked at Bristol Myers Squibb, Pfizer, Novartis and The Medicines Company where she had key roles developing blockbuster cardiovascular drugs such as Lipitor®, Diovan/Diovan HCT®, Lotrel® and Angiomax.. At Novartis, she led the malignant hematology franchise across Europe and was responsible for Glivec®, Tasigna®, Exjade® and Jakavi® generating over $2 billion in revenue across 38 countries. She later served as Global Lead for the Lung Cancer franchise managing a portfolio of seven products across research, development and launch phases.
Suman has held senior leadership roles across early and late-stage development, global launches, and commercial portfolio growth. She has served as CEO of Cambridge Epigenetix (UK) and as CEO and Co-Founder of Larkspur Biosciences a clinical stage immuno-oncology company. She serves on multiple biotech boards and is a Trustee & Board Member for Prostate Cancer Research UK and US.
Suman holds an MBBS from the University of Bombay and a Ph.D. in Virology from Harvard University in Virology and previously worked at McKinsey & Company in its healthcare practice.
Sanne de Jongh
OSE Representative and Board Observer
Sanne de Jongh
OSE Representative and Board Observer
Sanne is a Partner in the Life Sciences team at Oxford Science Enterprises (OSE). At OSE she is focused on the sourcing and structuring of new spinout opportunities from the University of Oxford, as well as supporting the existing Life Sciences portfolio. Prior to OSE, she was an investment manager at specialist transatlantic investor Gilde Healthcare, where she focused on European biotech investments, including Tagworks, ADCendo, Draupnir Bio and Calypso Biotech.
Prior to Gilde, Sanne was at Anterra Capital, a transatlantic Food and Ag Tech VC firm. Sanne began her career at M Ventures, the strategic corporate VC fund of Merck KGaA, focused on healthcare. She holds a BSc in Biochemistry from Leiden University with a minor in Neurology, and MSc in Biochemical Engineering from Delft University of Technology, the Netherlands. She serves as a director on the boards of OSE portfolio companies Sitryx, Orfonyx and MatchBio.
Dr Sally Dewhurst
OSE Representative and Director
Dr Sally Dewhurst
OSE Representative and Director
Sally is a Principal in the life sciences team at Oxford Science Enterprises (OSE) where she focuses on the creation of new biotech businesses, bringing deep oncology research expertise and experience translating cutting-edge science into company formation.
Sally was previously an Anderson Cancer Center Post-Doctoral Fellow at Rockefeller University in New York where her research focused on genetic instability at the very earliest stages of cancer development. Prior to this, she completed a Ph.D. at the Francis Crick Institute in London where she uncovered an important role for polypoid cells in driving cancer evolution.
Sally has contributed to published research in leading journals such as Nature Genetics, Nature Communications and Cancer Discovery. She has also studied corporate finance at NYU and consulted for The Solution Lab.
Dr Benedicte Menn
Board Observer
Dr Benedicte Menn
Board Observer
Benedicte is Senior Investment Manager at Oxford University Innovation (OUI), the technology transfer office of the University of Oxford. Since 2017, she has supported the formation of several Oxford spinouts, including MiroBio subsequently acquired by Gilead Sciences. Benedicte currently manages a portfolio of 40+ University spinouts and sits on the board of 10+ of them.
Before joining OUI, Benedicte co-founded a biotech spinout focused on therapeutics for neurological diseases. Benedicte holds a D.Phil. in life sciences from Paris University and a PMP® certification.
Driving the science
Scientific and Clinical Advisers
Dr Claire Harrison
Dr Claire Harrison
Claire graduated from Oxford University Medical School and became a consultant at the Guy’s and St Thomas Hospital in 2001, where she is now a deputy chief medical officer. The focus of her clinical work is myeloproliferative neoplasms (MPN), for which she has a national and international reputation. Key areas of interest are clinical trials and associated translational research. Her work has led to the approval of new therapies such a ruxolitinib, fedratinib, momelotinib and pacritinib and the first description of the link between molecular response and overall survival. In the past 10 years she has published widely (>300 academic articles) and she is the Deputy Editor in Chief of HemaSphere, a high ranking and widely regarded journal in hematology.
In addition, she has a strong interest in patient advocacy and founded the UK MPN group.
Claire was awarded the British Society for Haematology medal in 2023 and the Lifetime Achievement Award by European Haematology Association in 2026.
Dr John M. Lambert
Dr John M. Lambert
John joined the Dana-Farber Cancer Institute, Harvard Medical School, Boston, in 1981 to work on a series of ImmunoGen-funded programs to develop antibody-drug conjugates (ADCs) and immunotoxins as anti-cancer therapeutics.
When ImmunoGen, established independent research laboratories in Cambridge, MA in 1987, he went on to hold multiple roles at the company, eventually serving as Executive Vice President, Research and Chief Scientific Officer from 2008 until 2015, and later as Distinguished Research Fellow until his retirement in 2018. During his leadership, ImmunoGen invented ADC technologies that led to approved therapies including KADCYLA® for HER2+ breast cancer, ELAHERE® for ovarian cancer, and the anti-CD38 antibody that became SARCLISA® for multiple myeloma.
John holds a Ph.D. in Biochemistry from the University of Cambridge, UK and completed postdoctoral training at the University of California at Davis and at the University of Glasgow, UK. He has authored over 130 peer-reviewed scientific publications and has received multiple professional honours.